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Pernicious anaemia is caused by a deficiency in vitamin B12, due to atrophic gastritis, an autoimmune condition (immune system destroys self), in this case the parietal cells of the stomach that produce intrinsic factor, a glycoprotein that binds to vitamin B12 in the stomach and is essential for normal absorption of vitamin B12 in the small intestine into the blood

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In this guide, we’ll walk you through how to carefully self-administer subcutaneous (SubQ) and intramuscular (IM) injections, explain when each method is typically used, and share practical tips to help you feel confident and informed at every step