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Chem Res Toxicol 2020;33:162–71 [DOI] [PubMed] [Google Scholar] 111.Lin Z, Wu F, Lin S, Pan X, Jin L, Lu T, Shi L, Wang Y, Xu A, Li X.Adiponectin protects against acetaminophen-induced mitochondrial dysfunction and acute liver injury by promoting autophagy in mice

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However, the sub-pocket for the TYS of CCK-8 is more positively charged in CCK1R attributed to N98 2.61 , and R197 ECL2 contributes to a beneficial charge–charge interaction with TYS of CCK-8 (Fig