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For example, a meta-analysis of 29 studies reported children with ASD had a significantly lower dietary intake of B12 compared to controls [64], while another meta-analysis of 16 studies found plasma B12 concentrations significantly lower in ASD compared to controls, although evidence of potential publication bias was found [5]
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Biologic drugs target specific immune pathways, but patients may still suffer opportunistic infections and long‑term risks like cancer
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