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on the NF-κB pathway also revealed that LIPUS improved the condition of IL-1β-induced human chondrocytes by preventing the activation of the NF-κB signaling pathway, which further led to reduced expression of MMP-13 and metalloproteinase with thrombospondin motifs 5 (ADAMTS-5) in chondrocytes

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have provided additional evidence that resorcinolic acid saponins activate the extrinsic apoptotic pathway to induce cancer cell death in an A549 xenograft model