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Replying to @Angela Vitamin B12 supplements can trigger an acne-like eruption, as can vitamin B6 & biotin supplements. In contrast to acne, there are no comedones. Once the supplements are stopped, ...

In our study, one month of oral vitamin B12 significantly increased serum cobalamin levels, but the effect did not persist after three more months without supplementation

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A meta-analysis of patients from two large trials revealed that patients with normal kidney function may benefit from vitamin B12 supplementation for stroke prevention, whereas patients with impaired kidney function may not (235)