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Deacetylation involves removing acetyl groups using Histone deacetylases (HDACs), which make chromatin more condensed and cause gene suppression (Peng and Zhong, 2015)

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The association and dissociation of K:I are described by the k 1 and k 2 rates, while the formation of K:I cov from K:I or the formation of K:I from K:I cov are described by k 3 and k 4 , respectively