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Investigacion
Option:4.4oz
Although challenges such as blood–brain barrier delivery remain, emerging strategies, including gene therapy, TrkB agonists, and lifestyle interventions that elevate endogenous BDNF, highlight the translational potential of targeting BDNF to counteract neurogenesis and plasticity deficits in AD beyond conventional amyloid- and tau-focused approaches ( 3.2 Enhancing neurotransmitter release and synaptogenesis to counteract neurogenesis and plasticity deficits in AD AD is characterized by impaired neurotransmitter release and synapse loss emerging as key drivers of cognitive decline
