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The type of oligomerization loop in rhGPx3 mutant is mainly lined by hydrophilic residues (Thr-165, Ser-166, Asp-167, Arg-168, Trp-171 and Glu-172) and the surface of oligomerization loop is negatively charged (Figure 4b)

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S2A), surprisingly, NXP800 does not affect HSF1 or HSP70/72 expression at protein level after 24 h of treatment (Fig