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Understanding how GSH level and synthesis velocity depend on the sex hormones is an extremely important question since oxidative stress contributes to the risk for heart disease [8] and cancer [9] , and oxidative stress is reduced by GSH via the enzyme GPX [Figure 1]

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Upon oxidative stress, elevated levels of glutathione disulfides, the oxidized form of the antioxidant glutathione (GSH), were noted, along with a decrease in levels of reduced GSH