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Thus, considering the impairment in all three lines of defense against PC in diabetes, it is not surprising that PC plays a critical role in the pathogenesis of this disease ( 5 Protein carbonylation in diabetes: from peripheral tissues to pancreatic β-cells While the etiologies of T1D and T2D are somewhat different, increased OS, in particular in β-cells, plays a key role in both diseases (147–164)

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This was achieved even though only 57% of patients reached the highest CagriSema dose,” said Martin Holst Lange, EVP of development at Novo, in a statement