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Superimposing other ZF–CRBN structures, such as ZNF692, similarly not found engaged with ALV2 in our assays, also finds the compound blocking ZNF692 aZF1 binding, with leucine (L413) replacing the critical Helios serine (S133) that engages ALV2
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Due to the formation of DCX + cells in the SVZ and their clear ability to migrate, these neuronal cells are probably the most important source of new neurons in the cortex and striatum
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