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Patch electrodes with resistances of 2.5–3.5 MΩ were filled with a CsCl-based internal solution consisting of 140 mM CsCl, 2 mM NaCl, 10 mM HEPES, 5 mM EGTA, 2 mM MgCl 2 , 0.5 mM CaCl 2 , 2 mM Na-ATP, 0.5 mM Na-GTP and 2 mM QX-314, were used for the whole-cell recording configuration

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