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For ADCs such as Mylotarg, Blenrep, Trodelvy, and Camidanlumab, the future lies in creating more stable, tumor-specific linkers, site-specific conjugation for consistent DAR, and next-generation payloads with improved therapeutic windows, while bispecific ADCs and immune-modulating payloads are also advancing
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The results were notable across several dimensions: Glutathione restoration: Glutathione concentrations improved by 164% in muscle and by 225% in red blood cells, restoring levels to ranges not statistically different from young adults
