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In this pathway, D1-like receptors couple to G α q and stimulate PLC β , leading to diacylglycerol and IP 3 production, and the subsequent activation of Ca 2+ and PKC (Jin et al., 1998

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Professor Atherton has received travel sponsorship and/or honoraria or consultancy payments (made to his employer) from or undertaken clinical trials sponsored by Amgen, AstraZeneca, Boehringer Ingelheim, Eli Lilly and Novo Nordisk