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Where AOD 9604 targets fat cells directly, tirzepatide works through the incretin system, a network of hormones that regulate appetite, digestion, and insulin secretion from the gut level upward
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Structures shown in panels c – f were derived from data set 1/structure 1 and are similar in conformation to the related domains derived from data set 2/structure 2 (see Extended Data Table 2)
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