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IV doses of 25-400 mcg/kg for safety studies Important: These are experimental doses used in animal studies and cannot be extrapolated to other species due to significant differences in metabolism, pharmacokinetics, receptor expression, peptide degradation rates, and tissue distribution patterns

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Genetic Pathways and Personalized Response Variants in genes encoding methylenetetrahydrofolate reductase (MTHFR), transcobalamin, and intrinsic factor alter how efficiently your body absorbs and utilizes B12