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Uric acid does act as a potent antioxidant in the serum, and it is thought to contribute about 60% to the plasma antioxidant capacity in the body.[ref] Studies show that uric acid levels are lower in people with Parkinson’s disease and that high uric acid levels are protective against Parkinson’s.[ref][ref] There is also a link between quicker progression in Alzheimer’s with low uric acid
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In addition, protein-protein interactions of GPx1 with TRAF prevents the formation of the active TRAF/ASK1 complex to prevent apoptosis [148] (Figure 5)
