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At this point, there is insufficient evidence to recommend B12 supplementation for fatigue beyond correcting a deficiency
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The requirement for increased nAb concentration to inhibit cell–cell spread may be associated with avidity effects of extended cell surfaces interacting with one another (in contrast to a viral surface with potentially less available surface for interaction), although other factors such as the restricted access of nAbs to interacting cell surfaces could also contribute 74,75
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