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217 Notably, mutant PS1 disturbs this mechanism because mutant PS1 significantly increases the transcriptional activity of p53

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doi: 10.1016/j.jneuroim.2011.08.019 75 WolfSDDittelBNHardardottirFJanewayCAJr

GSH achieves this by directly reducing disulfide bonds in cytoplasmic proteins to cysteines