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FOXO4-DRI can selectively and potently target senescent cells for p53-dependent apoptosis Given the reported pro-apoptotic role of active p53 when recruited to mitochondria, we next assessed the effects on senescent cell viability

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Cataract, the leading cause of reversible blindness globally, involves the gradual opacification of the crystalline lens, primarily driven by cumulative oxidative stress and protein aggregation within the lens fibers