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Mitochondria-dependent apoptosis pathway: metformin can induce the loss of mitochondrial membrane potential and release apoptosis-related factors such as cytochrome C, thereby activating the caspase cascade and ultimately leading to apoptosis (64, 65)

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10.1159/000530495 Summary Keywords Phyllanthus urinaria L., liver disease, viral hepatitis, liver fibrosis/cirrhosis, hepatocellular carcinoma Citation Liu L, Wang B, Ma Y, Sun K, Wang P, Li M, Dong J, Qin M, Li M, Wei C, Tan Y, He J, Guo K and Yu X (2024) A review of Phyllanthus urinaria L