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Problematisch wird es nur, wenn das Verhältnis zwischen freien Radikalen und Radikalfängern nicht mehr stimmt

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The predicted P eff value for D-NIe-Tyr-Ile-NH-(CH 2 ) 5 -CONH 2 (1.53) is intermediate between the predicted P eff values for enalapril (1.25) and piroxicam (2.14), two orally bioavailable drugs