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✳️ Translational evaluation of Gelsectan® effects on gut barrier dysfunction & visceral pain in animal models & irritable bowel syndrome with diarrhoea ✓ 7-day oral administration of Gelsectan® prevented the stress-induced rectal
The design rationale is discussed further in de Keizer, Trends in Molecular Medicine , 2017, volume 23
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Although FMT is potentially effective in many microbiota-related disorders, helping establish trans-kingdom equilibrium between gut fungi, viruses and bacteria to promote the restoration of microbial homeostasis (McSweeney et al., 2020), the effect of FMT depends on several factors, including the bacterial load and microbial composition and function of the recipient and the donor, the physiological and genetic factors related to the recipient and the donor, and FMT preparation and route of administration (Vermeire et al., 2016
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