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If they had at least a 50% reduction in their HRSD 17 scores, from baseline to exit, they were categorized as responders, otherwise they were nonresponders

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Hewlett Packard, Palo Alto, CA, USA) inserted into the superior sagittal sinus, portal vein, inferior vena cava and abdominal aorta at the level of the bifurcation at 30 min after isoprenaline 75 mg/kg sc (providing saline or BPC 157 given at 5 min after isoprenaline)