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The SIC was 148.62 ± 17.63 μg/L (GD I group), 72.33 ± 12.08 μg/L (GD II group), and 75.24 ± 7.94 μg/L (NC group), respectively, with statistically significant differences among the three groups (P 0.05)
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However, even with multiple antiemetic medications administered prior to high-dose cisplatin (≥50 mg/m 2 ), about 30% of cisplatin-treated patients experience both nausea and vomiting while another 39% experience just nausea (Stinson et al., 2017)
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