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For example, activation of the limbic and paralimbic systems, which are responsible for behavioral and emotional responses, are thought to contribute to distress signaling and complications of tinnitus, such as cognitive, mood, and sleep disorders, in some individuals

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Fingolimod ameliorates acetic acid-induced ulcerative colitis: an insight into its modulatory impact on pro/anti-inflammatory cytokines and AKT/mTOR signalling