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EGCG suppressed the expression of several proinflammatory cytokines and chemokines including IL-1Ξ², IL-6, IL-7, TNFΞ±, LIF, MCSF, Oncostatin M, MCP-1, MCP-2 and IL-8 in primary human chondrocytes through the inhibition of NFΞΊB and MAPK signaling pathway [16, 54]
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