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It has a genuine FDA-approval history rather than being a novel "research chemical," but no FDA-approved finished product remains on the market, so it is supplied only through compounding pharmacies and prescribed off-label in adults for growth-hormone-axis support, general wellness, or anti-aging purposes rather than its original pediatric indication

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β-Hydroxybutyrate, a ketone body, potentiates the antioxidant defense via thioredoxin 1 upregulation in cardiomyocytes