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Read part one here, and part two here

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Key takeaways: High B12 on your labs while supplementing signals successful absorption, not a health problem B12 is water-soluble, so your kidneys filter and excrete any excess naturally, with no toxicity risk Lab reference ranges were built from non-supplementing populations, so your numbers will look different by design High B12 without supplementation warrants a clinician follow-up to rule out liver, blood, or kidney conditions Long-term Metformin use can deplete B12 by blocking gut absorption