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Xeomin contains botulinum toxin type A, a protein purified from the bacterium Clostridium botulinum

and B12

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84,87 Another trial with 67 participants found a hops extract standardized to supply 100 mcg of 8-prenylnaringenin per day reduced hot flashes more than placebo after six weeks, but the difference between hops and placebo disappeared after 12 weeks