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Mild irritation is possible, especially when first starting use
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AnkB-deficient animals have sinus bradycardia, a prolonged QT interval, and other myocardial electrical phenotype changes, promoting myocardial mechanical remodelling as well as premature death, which is related to the low expression of β-catenin in the intercalated disc and high expression in the cytoplasm caused by the loss of AnkB
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