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Biotechnol 109 WangY.ZhangX.ZhuangW.YuY.SunX.WangH.et al (2022)

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“Implementing antimicrobial stewardship in the context of care to persons with CF provides benefit in this complex patient population.” Despite national consensus guidelines for antibiotic treatment for pulmonary exacerbations in people with CF, prior research and systematic reviews have repeatedly demonstrated a longstanding lack of sufficient evidence for empiric antibiotic therapy recommendations, leading to a significant variation in how antibiotics are prescribed across CF care centers in the United States