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The Effect of Coenzyme Q10 on Serum Glutathione... : Turkish Journal of Dermatology
In these contexts, astrocytes may shift from a neuroprotective role to one that exacerbates neuronal dysfunction, potentially due to downregulated expression of lactate dehydrogenase A (LDHA), a key glycolytic enzyme, which impairs lactate shuttling by inhibiting large conductance Ca 2+ activated potassium channel (BK channel)-mediated neuronal hyperpolarization (Yao et al., 2023)
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This is not necessarily dangerous, but requires understanding that blood sugar effects may be unpredictable
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