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These promising results should encourage us to keep studying mitochondria alterations in the different CNS cell types to identify specific pathways at the basis of pathological dysfunction and to develop cell-targeted therapies

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Finally, the recombinant protein was eluted with 10 ml of elution buffer [50 mM Tris-HCl, pH 8.0, 0.5 M NaCl, and 500 mM imidazole] and dialyzed two times