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“For a condition like melasma, which is environmentally dependent, it is a chronic struggle that will unfortunately worsen at times.” Also, if you experience recurrent hyperpigmentation stemming from a repeat cause—for instance, acne continuously pops up, creating new dark spots—then a visit to the dermatologist is recommended so you can address the underlying issue (in this case, the acne)

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Rigorous controls and antibody optimization are essential to prevent false results and minimize nonspecific binding