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Eric Topol of Scripps Research Translational Institute was more direct: "These peptides have no data to support their safety and efficacy." The clinical proponents argue that the FDA's safety concerns — immunogenicity risk, impurity risk, organ toxicity — are theoretically valid but speculative in practice

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PubMed 33894838 (doi:10.1016/S0140-6736(21)00845-X) Novo Nordisk A/S