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Frontiers | G6PDH as a key immunometabolic and redox trigger in arthropods

For the analysis of external dataset 27 (GEO accession code GSE214411) including EuE from women with endometriosis ( N = 3) and EuE from women without endometriosis (controls, N = 3) in the proliferative phase of menstrual cycle, we followed the same steps of the analysis from quality control to cell clustering as for our dataset, and filtered out cells with ribosomal reads more than 15%

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This animal model also exhibit a dysregulation of Nrf2-dependent antioxidant responses in the vasculature, which promotes the development of marked endothelial dysfunction and endothelial apoptosis in the presence of increased oxidative stress [281], mimicking the aging phenotype