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Thus, both these techniques give concentrations of the same order, regardless of potential problems such as cross-contamination between compartments or fractions during sample preparation
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It is also worth noting that a large cluster of long heparan polymers on the cell surface could be associated with multiple dimeric c-MET/HGF complexes and in principle induce the higher-order oligomerization of c-METs, and potentially lead to the formation of even larger biomolecular condensates on the cell membrane
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