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As a consequence of its disease-specific pathology, diabetes mellitus is now the leading cause of new blindness in people 20–74 years of age and the leading cause of end-stage renal disease (ESRD) in the developed world

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The administration of liproxstatin-1 or ferrostatin-1, which are specific compounds that suppress ferroptosis, shields intestinal epithelial cells from peroxidative damage and aids in the recovery of intestinal barrier integrity (173, 174)