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People on diabetes medications Vegetarians (and vegans) Elderly People on anti acids People with Crohn’s Disease, Ulcerative Colitis, Celiac Disease or Irritable Bowel Syndrome (IBS) Women with a history of infertility and miscarriage How often should one get vitamin B12 injections

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About 60% of users who experience GI side effects report that evening dosing significantly reduces their perception of discomfort