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Research has indicated that TPGS dosages up to 0.5% ( w / v ) are well tolerated in in vitro cell models and have demonstrated encouraging outcomes in improving drug retention at therapeutic levels without significantly harming normal cells [377]
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However, manufacturing companies, including Novo Nordisk and Eli Lilly, do not guarantee the sterility of GLP-1 drugs like semaglutide and tirzepatide beyond the expiration date
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