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[DOI] [PubMed] [Google Scholar] 173.Salinas-Navarro M., Alarcón-Martínez L., Valiente-Soriano F.J., Ortín-Martínez A., Jiménez-López M., Avilés-Trigueros M., Villegas-Pérez M.P., de la Villa P., Vidal-Sanz M

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While this initial hormonal response may confer transient anti-inflammatory and neuroprotective effects, conditions of chronic stress or frequent seizures lead to a dysregulation of the HPA axis’s negative feedback mechanisms, culminating in persistent hypercortisolemia