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Moreover, phyllanthin decreased the protein expression of TNF-α and NF-κB p65, and reduced collagen deposition to counteract ECM synthesis

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A striking example is a 2024 case report involving a 47-year-old commercial airline pilot who developed acute brain fog manifesting as somnolence, impaired concentration, and mental fatigue alongside worsened abdominal distress shortly after initiating an over-the-counter probiotic supplement containing 16 strains