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IL-6 increases the biogenesis of exosomes by upregulating gene expression without changing the pre-miRNA-223 expression ( miRNA-223 enriched exosomes are delivered to the liver and inhibit the expression of miR-223 target pro-fibrotic genes like Igf1r, Cxcl10, Taz , and Nlrp3

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The hair growth cycle is long, consisting of anagen (growth), catagen (transition), and telogen (resting) phases