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1b): 7,8,9,10,11,12,15,17,19,30 During the oxidative half-reaction the thiolate group of the reduced glutaredoxin attacks the GSSR disulfide bond, yielding the first product (RSH) and the glutathionylated glutaredoxin Grx(SSG) as an intermediate

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There are likely many undiagnosed Wilson disease patients 1 in 10,000 to 30,000 individuals have Wilson disease and 1 in 90 individuals are carriers