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Basically, cyanocobalamin needs to be broken down to cobalamin and cyanide in order to convert to the active form of B12, and some researchers have concerns about the effects of cyanide accumulation in the body with long-term use of cyanocobalamin — but the jury’s still out on whether that’s a cause for concern
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High levels are associated with cardiovascular risk and may also suggest a vitamin B12 or folate deficiency
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