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Folic acid intake from food and supplements should not exceed 1,000 micrograms (μg) daily in healthy individuals because large amounts of folic acid can trigger the damaging effects of vitamin B12 deficiency [7]

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You may want to talk with a doctor about B12 shots if you regularly experience: Persistent fatigue and lethargy Muscle aches and joint pain Loss of appetite Nausea, constipation, diarrhea, or cramping Poor memory or difficulty concentrating Mood swings Can B12 Injections Help With Mood Enhancement and Mental Clarity