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This indicates that MLCK-dependent intestinal barrier loss promotes local, terminal differentiation of antigen-specific T cells during evolution of GVHD

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In the VITACOG trial, high-dose B vitamins in older adults with mild cognitive impairment and elevated homocysteine reduced atrophy in the gray matter regions most vulnerable to Alzheimer’s disease, with the placebo group losing about 3.7 percent and the treatment group about 0.5 percent over two years