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For a severe migraine that has lasted at least three days, doctors may try a cocktail that includes some or all of the following: IV fluids An NSAID called ketorolac (given by injection or infusion) A dopamine receptor blocker, such as prochlorperazine, metoclopramide, or chlorpromazine Valproate, which is usually used to treat convulsions Dihydroergotamine, a commonly used migraine drug Doctors may also choose other combinations of migraine medications to treat your headache

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This work was done on structured proteins