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For these reasons, focusing on 1-year outcomes among new recipients is important to capture the well established benefits of methadone for people retained in treatment.20 Our comparative results also reflect differences in drug-use patterns and the severity of opioid use disorder among SOS recipients that could not be accounted for using administrative health data, and differences in the goals of SOS and OAT programmes.19,21 For example, people receiving SOS had substantially higher rates of medical comorbidities at baseline than individuals commencing methadone, suggesting that SOS use was concentrated among individuals with high acuity and those with serious medical complications from drug use